Research interests:
- Gene therapy
- Vectored immunoprophylaxis (VIP)
- Oncolytic virotherapy
- Viral vectored vaccines
- Viral pathogenesis
Selected Publications: PubMed
Dr. Sarah Wootton, BSc, PhD
Associate Professor, Pathobiology
Ontario Veterinary College
University of Guelph
PhD – Biosketch
Sarah Wootton is an Associate Professor of Veterinary Virology in the Department of Pathobiology at the Ontario Veterinary College, University of Guelph. She obtained her Bachelor of Science degree in biochemistry from the University of Guelph in 1997, and her PhD in Veterinary Virology from the same institute in 2002. Subsequently, she moved to the Fred Hutchinson Cancer Research Center in Seattle, WA to study oncogenic retroviruses and lung gene therapy in the laboratory of Dr. Dusty Miller. During this time, she was supported by postdoctoral fellowships from both the CIHR and NSERC. In September 2007, she joined the faculty at the University of Guelph. Dr. Wootton’s research interests are currently focused on the molecular pathogenesis of retrovirus-induced lung and nasal cancer in sheep, gene therapy for lung and liver diseases, oncolytic virotherapy and viral vectored vaccines.
Curriculum vitae:
B.Sc. Biochemistry 1997 University of Guelph
Ph.D. Virology 2002 Ontario Veterinary College,
University of Guelph
Postdoctoral Training 2007 Fred Hutchinson Cancer Research Center,
Seattle WA
Graduate Students and Staff
Jondavid de Jong, PhD (Postdoctoral fellow)
“Nuclease-based gene therapy for permanent correction of CF lung disease”
Lisa Santry (PhD program)
“Improving the oncolytic and immunomodulatory properties of recombinant Newcastle Disease Virus”
Jacob van Vloten (PhD program; co-advised with Dr. Byram Bridle)
“Role of immunogenic cell death in ORF virus-induced oncolysis and immune stimulation”
Maria Rosales Gerpe, MSc (PhD program)
“Tissue Tropism and Transformation Determinants of Jaagsiekte Sheep Retrovirus and Enzootic Nasal Tumour Virus”
Joelle Ingrao, DVM, DVSc (PhD program)
“Development of a recombinant parapoxvirus vaccine against Toxoplasma gondii”
Laura van Lieshout (PhD program)
“Development of a novel hybrid gene therapy vector using CRISPR-mediated gene targeting for the correction of alpha-1 antitrypsin deficiency”
Betty-Anne McBey, MSc
Flow cytometry, propagation of viruses, molecular biology